Mechanism of salvianolic acid B neuroprotection against ischemia/reperfusion induced cerebral injury

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Mechanism of salvianolic acid B neuroprotection against ischemia/reperfusion induced cerebral injury

The purpose of this study was to evaluate the cerebral protection of salvianolic acid B (Sal B) against cerebral I/R injury and investigate the underlying mechanism. As shown by 2,3,5-Triphenyltetrazolium chloride (TTC) staining and magnetic resonance imaging (MRI) analyses, Sal B significantly reduced cerebral infarct size, and accompanied with improved neurobehavioral functions as indicated b...

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Neuroprotective Effect of Salvianolic Acids against Cerebral Ischemia/Reperfusion Injury

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Ischemic stroke (IS) is characterized by the sudden loss of blood circulation to an area of the brain, resulting in a corresponding loss of neurologic function. It has been a worldwide critical disease threatening to the health and life of human beings. Despite significant progresses achieved, effective treatment still remains a formidable challenge due to the complexity of the disease. Salvian...

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ژورنال

عنوان ژورنال: Brain Research

سال: 2018

ISSN: 0006-8993

DOI: 10.1016/j.brainres.2017.11.027